Nonetheless, mouse data suggest that even a low level of expression (~5%) might still be beneficial.
Together, the human and mouse data suggest that BRCA1 not only functions as a tumour suppressor, but is also required for development of resistance to therapy.
Mouse data suggest that in permissive strains, ES cells can be derived from embryos at around E4 E4.5 of development, a stage that has been termed the naive stage of embryogenesis (Nichols and Smith, 2009; Boroviak et al., 2014).
These mouse data suggest that, whatever the duration of dietary restriction, individuals will not adjust to the new level of intake and will face a constant struggle to remain compliant with dietary restriction interventions.
The mouse data suggest that prior degenerative pathology increases risk for acute cognitive impairment even before baseline cognitive impairment has emerged and we propose that synaptic loss will predict susceptibility to delirium in humans.
This is consistent with previous mouse data suggesting that IL-13, via IL-13Rα1, is involved in baseline IgE maintenance but not IgE responses to T cell-dependent antigens (Munitz et al., 2008).
The transgenic mouse data suggests that increased SK3 function results in diminished cognitive function, consistent with the hypothesized direction, but not the most direct test of whether reduced function improves cognition.
Luscher said the mice data suggest this loss of a braking system is a cause of addictive behavior.
Compared to the profile of VEH mice, data suggest a 2 h-longer peak at wake-up, with the relative minimum of activity being shifted onward (from 12 h to 14 h) in DAT-i ones.
This confirms mice data suggesting the need of blood brain barrier disruption for myeloid progenitors to penetrate into the brain and differentiate into microglia-like cells [ 3, 29, 99, 100].
