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"The jail was made of wood and lined with heavy timbers set endways and driven full of nails, so that a mouse could not have escaped.
The mouse could not subsequently be found, so the decision was taken to rebook the passengers on different flights because of fears the animal might damage the electric wiring.
Restraint stress was accomplished by placing the animal in a ventilated plastic chamber in which the mouse could not move to any significant degree, for 6 h.
Therefore, mutational analyses for mouse could not be performed.
Thus, this mouse could not be used further.
End-stage disease was determined when the mouse could not right itself after 30 sec when placed on its side.
Similar(49)
I was to a party one nite (private) and they finely got me to sing a few numbers for them and the mouse couldn't take her eyes off me.
After iohexol injection (II), the vascular system of the experimental mice could not be imaged.
Thus, although physiological estrogen levels in young ROP Os/+ mice could not prevent the development of glomerulosclerosis, estrogen deficiency accelerated the progression of glomerular scarring in this mouse strain.
Previous studies using CRISPR-based genome editing methods to generate point mutations in mice could not achieve 100% efficiency and resulted in mosaicism (Inui et al., 2014; Wu et al., 2013).
However, knockout of parkin in mice could not faithfully recapitulate the PD phenotype, raising the question of the physiological function and the pathologic role of parkin in PD (Dawson and Dawson, 2010; Johnson et al., 2012; Shin et al., 2011).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com