Their distribution is somewhat more extensive in CA3 of mice, comprising a larger portion of lately formed CA3 pyramids (Slomianka and Geneser 1997).
To investigate if allelic heterogeneity contributes to phenotypic variability, we analyzed an allelic series of Col4a1 and Col4a2 mutant mice comprising a splice site mutation and seven glycine missense mutations within the triple-helix-forming domains (six in COL4A1, one in COL4A2), and one missense mutation in the globular NC1 domain of COL4A1 (Fig. 1A).
Notably, 10 days after damage TA muscles of MP-depleted mice comprised a relatively high number of capillaries.
As shown in Fig. 5a, the normal islet architecture of control mice comprised a large core of insulin-positive beta cells ringed by a mantle of glucagon-positive alpha cells.
However, tumors from septic mice comprised an increased proportion of monocytic-myeloid-derived suppressor cells (Mo-MDSC).
A full 72 hours of EEG were manually screened for SWDs for each mouse, comprising 24 hours before drug delivery and 48 hours afterward.
We systematically study the evidence on unspliced transcripts available in EST annotation tracks for human and mouse, comprising 104,980 and 66,109 unspliced EST clusters, respectively.
A single intravenous injection of AAV9-ADAR2 in AR2 mice, which comprise a mechanistic mouse model of sporadic ALS, effectively prevented progressive motor dysfunction and death of motor neurons by enhancing ADAR2 activity.
Both QTLs share an area which in cattle and mouse comprises 97 and 100 genes, respectively.
In summary, the C/EBPβΔuORF mouse comprises the first genetic animal model that confirms the physiological significance of uORF translation in vivo and its action as a molecular switch driving cell fate decisions by modulating isoform expression ratios.
