Sentence examples for mouse cerebrum transcriptome from inspiring English sources

To understand the molecular mechanism of cerebral development, we compared dynamics of mouse cerebrum transcriptome through three developmental stages using high-throughput RNA-seq technique.

Conclusions/Significance: Our studies show that the AAV-modified thalamus can be used as a 'built-in' central node network for widespread distribution of lysosomal enzymes in the mouse cerebrum.

Our studies show that the AAV-modified thalamus can be used as a 'built-in' central node network for widespread distribution of lysosomal enzymes in the mouse cerebrum.

To our knowledge this is the first study demonstrating the potential of thalamic gene delivery to achieve global distribution of a lysosomal enzyme throughout the mouse cerebrum.

Absolute quantifications of ATP, ADP, and AMP in the mouse cerebrum were performed by CE-MS and revealed massive reductions in the levels of ATP and ADP (both p<0.005), but not AMP during the seizure (Fig. 1b and Table 1).

Three libraries were generated from the mouse cerebrum at infancy, adolescence and adulthood, respectively.

Myelin was generated approximately from the postnatal week 2 in the mouse cerebrum.

Finally, the mC level observed in mouse cerebrum (cerebral cortex) remains roughly constant until p14.

Preparations of total RNA, reverse transcription and cDNAs synthesis from mouse cerebrum were performed as described previously (52).

We do not know if levels of mitochondrial Lon or TFAM were altered in our aged mouse cerebrum.

Consequently, we identified 15,344, 16,048 and 15,775 genes expressed in the mouse cerebrum at infancy, adolescence and adulthood, respectively (with cutoff value of 5 reads/gene).