Sentence examples for mouse cerebellar development from inspiring English sources

By analyzing gene expression profiles of CDT-DB during postnatal mouse cerebellar development, a developmentally regulated transcript was identified (CDT-DB ID number CD00130; DDBJ/GenBank/EMBL accession number BP426385).

Homologous genes were identified between mouse microarray chip probes and the human genome, resulting in 6790 homologous genes in the mouse cerebellar development data series and 6356 homologous genes in the mouse lung development data series.

The present study identified a developmentally regulated transcript, PLD4, after searching the cerebellar development transcriptome database (CDT-DB) for characteristic spatiotemporal gene expression patterns during mouse cerebellar development [25].

Comparison of mouse cerebellar development and medulloblastoma demonstrates a shared miRNA mRNA co-expression program for brain-specific neurologic processes such as synaptic transmission and exocytosis, in which miRNA target expression increases with the accumulation of multiple miRNAs in developing cerebellum and decreases with the loss of these miRNAs in brain tumors.

Extrinsic signalling has previously been implicated in some aspects of mouse cerebellar development.

In contrast to what is suggested by Affymetrix, we did retain DEX genes in the Alternative Splice analysis because we were not only interested in alternative splicing events, but also in alternative transcription, as this was shown to occur more frequently than alternative splicing during mouse cerebellar development (Pal et al., 2011).

In contrast, ∼50% expression of MDM2, as in Mdm2+/Δ7-9 mise, isufficientnt for cerebellar development to proceed normally, thus illustrating the sensitivity of this process to the level of MDM2.

Regardless, Syne1-mutant mice present with normal cerebellar development.

On the other hand, animal models have shown that severe deficiencies in motor coordination in BDNF knockout mice are linked to abnormal cerebellar development [ 53, 54].

In order to examine whether Mib1 is required for cerebellar development, we bred Mib1f/f mice with hGFAP-cre transgenic mice, in which Cre recombinase is expressed in the Bergmann glia and granule cells, but not in the Purkinje cells, in the cerebellum [36].

After establishing that neuronal DG is not necessary for cerebellar histogenesis, we next evaluated the role of glial DG in cerebellar development by using mice with deletion of DG from both neuronal and glial cells.