Sentence examples for mouse cells lacking from inspiring English sources
Blasco, M.A. et al. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.
A similar response to oxidative stress was detected in mouse cells lacking a DNA break sensing molecule, PARP-1 [13] and PARP-1−/− MEFs display abnormal telomeres and chromosome instability.
An interesting study by Blasco and collaborators [40] has reported a reduction in centromeric repeats in mouse cells lacking the Dnmt3a and Dnmt3b DNA methyltransferases, suggesting DNA methylation at the centromeric heterochromatin to be an important mechanism to suppress "illicit" centromere mitotic recombination and to maintain centromere integrity.
Dramatic methylation losses are observed in plant and mouse cells lacking Lsh (lymphoid specific helicase), predominantly at repetitive sequences and gene promoters.
The involvement of Pol κ in HR was unexpected, as chicken DT-40 and mouse cells lacking this TLS polymerase have shown no phenotype upon exposure to ionizing radiation [32,33].
They described that human or mouse cells lacking AIF would exhibit high lactate production and enhanced dependency on glycolytic ATP production due to severe reduction of ETC complex I activity.
This data is consistent with previous findings in vivo in the mouse model that mouse ES cells lacking Gata2 could generate certain blood lineages, such as erythrocytes [ 10].
Although Ostapcuk and co-workers' study focused on the interplay between ADNP, CHD4 and HP1, the researchers found many fewer genes upregulated in mouse ES cells lacking ADNP than in those lacking all three HP1 isoforms.
In contrast, we did not find any decrease in H3K9 methylation in mouse ES cells lacking Dicer.
However, mouse ES cells lacking nanog can participate extensively in chimera formation, and at least in vitro, nanog positive and negative ES cells can interconvert.
The ectopic expression of latexin in mouse lymphoma cells lacking latexin expression show remarkable suppression of growth in vitro [ 10].
