Sentence examples for mouse brain suggest from inspiring English sources

Moreover, indicators of altered osmoregulation in Mecp2-null mouse brain suggest another link to changes in brain size, potentially caused by neurons and astrocytes.

Our findings of aberrant phosphorylated-α-synuclein accumulation in α-Gal A-deficient mouse brain suggest that its metabolism relies on, at least in part, functional α-Gal A. Previous studies have indicated the importance of intact ALP function for the efficient degradation of α-synuclein, including several experimental models of lysosomal storage disorders [ 24, 28– 31, 44– 44].

The long retention of these ligands in the normal mouse brain suggests that there may be high binding for these probes in the brain not associated with Aβ plaques.

In conclusion, we found a large number of protein expression differences throughout the entire lifespan of APP23 mice, beginning at ED16, a phase where neurogenesis is predominant in the developing mouse brain suggesting an early impact of transgenic APP.

Early studies on mouse brain suggested that there are between ~10,000 [ 18] and ~100,000 [ 41] transcript species per cell.

Furthermore, this interaction occurs at the synapse and is particularly evidence in adult mouse brain suggesting a role in synaptic plasticity.

Satb1 was identified in our genome-wide microarray screen as a gene downregulated in Lhx6-deficient mouse brain, suggesting that its expression depends on Lhx6 activity.

Our in situ hybridization shows that SLC17A9 mRNA is widely expressed in the mouse brain, suggesting that neurons from most brain regions may have the capacity to store ATP in vesicles.

The finding of unusually high amounts of PrPres in neoplastic lymphoreticular tissues of vCJD mice, in a range comparable to that of the human and mouse brain, suggests that rapidly growing lymphoreticular tumors accumulate PrPres at a high rate.

We did not appreciate any accumulation of autophagosomes in α-Gal A-deficient mouse brain, suggesting that the increase in LC3 immunoreactivity observed by IHC in Figure  1 may be localized to lipid-containing aggregates of undigested autophagic substrate.

Thus, an inverse correlation between RanBP9 and spinophilin, which is a marker of spines in different regions of mouse brain, suggests loss of spines may be at least partially due to RanBP9.