In any case, two of our main observations in mice deficient in PRKG1 in the brain, namely reduced REM sleep and EEG amplitude, have been made before in animals with impaired NO signaling [32] [34], implicating that the NO-cGMP-PRKG1 pathway might indeed be involved in sleep regulation.
Finally, we have measured aberration variations in thick biological tissues, namely human skin biopsies and mouse brain slices.
Recently, Juhila et al. described the miRNA expression patterns in the two regions of interest for antidepressant treatment response, namely, the prefrontal cortex and the hippocampus, of the mouse brain.
Namely, CDT2 was highly expressed in mouse/rat testis, spleen, and lung tissues, and modestly expressed exclusively in mouse brain, and a weak signal was observed for the remaining mouse/rat tissues (Fig. 6B and C).
Story No. 2: "Scientists Map Mouse Brain".
A mouse brain is the size of a peanut.
"They said putting the mouse brain on line would accelerate brain research throughout the world," Mr. Allen recalled.
Each strand was virtually invisible, about the size of four mouse brain cells.
The mouse brain atlas can be accessed without charge at www.brainatlas.org.org
a Mouse brain, b shale sample.
The results showed that irradiation of mouse brain with 2 Gy of 12C6+ ion or 60Co γ-ray significantly diminished mouse body weight and level of serum GH.
