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A combination of QRT-PCR confirmation in human hypothalamus and neuroanatomical screening in the mouse brain identified a single factor, IGFBP3 that is coexpressed with HCRT in both humans and mice and present in only a few other brain areas.
The proteomic assessment of the mouse brain identified 4878 unique peptides belonging to 1359 individual protein species in the wild type and 4311 unique peptides belonging to 1213 individual protein species in the mdx- 4cv phenotype.
Analysis of 3′UTRs and in utero over-expression of pre-miR-153 in fetal mouse brain identified Nfia (nuclear factor-1A) and its paralog, Nfib, as direct targets of miR-153.
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A global microarray screen of scrapie-infected mouse brains identified a limited number of genes undergoing transcriptional elevation well before the clinical onset of disease.
Survival of transplanted F3.Akt1 hNSCs in ICH mouse brain was identified by human nuclear matrix antigen (hNuMA)- or LacZ/β-gal-positive reaction.
A recent study on mouse brain has identified specific expression patterns of TLR7 and TLR9 expression in developing brain, which has been linked to the development of the central nervous system of vertebrates [ 46].
This study revealed spatial specificity in sex-biased transcription in the mouse brain, and identified 173 sex-biased genes in the striatum; 19 in the neocortex; 12 in the hippocampus and 31 in the eye.
Finally, the researchers mined a comprehensive atlas of genes expressed in the mouse brain to identify a cell surface receptor, called Npy1, which is expressed exclusively in dentate gyrus granule cells, and found that activating this receptor in normal mice with a synthetic peptide that selectively binds to it caused the same learning-induced memory loss seen in the other experiments.
Epub 2013 Oct 2. PMID: 24094102; PMCID: PMC3800182. of mouse and human brain identifies target genes in Alzheimer's disease.
In the itr1aΔ itr3cΔ mutant-infected mouse brain, we have identified 830 SDEG (552 genes up-regulated; 278 genes down-regulated).
The primary parts of the mouse brain can be identified soon after the neural groove, neural plate and head process stage at E7.5, and by day E14 has the typical anatomical layout of a mammalian brain.
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