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Surprisingly, we found that Nfatc1 is also expressed in mouse brain, having the highest expression levels in the granular and glomerular cell layers of the olfactory bulb.
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Acquisition of light microscopic data at 1-micrometer resolution for an entire mouse brain has been developed.
Pten deletion in the mouse brain has revealed its role in controlling cell size and number.
The distribution of MORs in the mouse brain has previously been investigated using immunohistochemistry and molecular biology [46].
Second, we have shown that aged female mouse brain has 65% more in vitro γ-secretase activity at 24 months compared to male mice.
Recent phenotypic characterization of Sez-6 null-mutant mouse brain has revealed a role for Sez-6 in specifying dendritic branching patterns of cortical neurons [4].
Comprehensive studies on miRNA expression throughout the mouse brain have been published [39], [40], but comparable studies in rats are lacking.
Moreover, preferential expression of TIP60 in the mouse brain has been reported [18] and a recent study reported Bap55 as a chromatin remodeling factor that functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting in Drosophila [70].
However, there are clear species and/or tissue differences with respect to the effects of PINK1, as experiments in mouse brain have not revealed any obvious changes in mitochondrial morphology in the absence of exogenous stressors [18].
While genetic deletion of EphBs from mouse brain has been found to result in fewer dendritic spines [16] and excitatory synapses [22], less is known regarding how reduced EphB expression in individual neurons in a more intact preparation impacts dendritic protrusion length.
The relative penetration of PMM and Trimelamol into mouse brain has therefore been examined.
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