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Comprehensive studies on miRNA expression throughout the mouse brain have been published [39], [40], but comparable studies in rats are lacking.
However, there are clear species and/or tissue differences with respect to the effects of PINK1, as experiments in mouse brain have not revealed any obvious changes in mitochondrial morphology in the absence of exogenous stressors [18].
Neuronal connections in the mouse brain have been investigated more thoroughly than in virtually any other mammalian species.
Two studies in the healthy adult mouse brain have revealed significant regional variations in the distribution of these molecules.
It has not been previously reported that gliomas induced with the same genetic alterations in different regions of the mouse brain have distinct gene expression.
Routes of transfer within mouse brain have been characterized by Iliff et al. using imaging of a number of different fluorescent markers [ 143].
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Acquisition of light microscopic data at 1-micrometer resolution for an entire mouse brain has been developed.
Pten deletion in the mouse brain has revealed its role in controlling cell size and number.
The distribution of MORs in the mouse brain has previously been investigated using immunohistochemistry and molecular biology [46].
Second, we have shown that aged female mouse brain has 65% more in vitro γ-secretase activity at 24 months compared to male mice.
Recent phenotypic characterization of Sez-6 null-mutant mouse brain has revealed a role for Sez-6 in specifying dendritic branching patterns of cortical neurons [4].
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