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Williams, R. W. Mapping genes that modulate mouse brain development: a quantitative genetic approach.
In summary, our results indicate detrimental effects of developmental caffeine exposure on mouse brain development.
Tasks can be mundane, such as daily cage cleaning, or leading edge, such as DNA analysis of genes involved in mouse brain development.
Hagelkruys, A. et al. A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.
In utero electroporation (IUE) is a simple and rapid approach to in vivo investigate exogenous gene function in mouse brain, and intensive studies using IUE have greatly contributed to analyze the characterization of specific steps during mouse brain development.
The Prenatal Mouse Brain Atlas is the only comprehensive book available for studies of mouse brain development from early embryonic to late fetal stages.
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TRIM32 is involved in the regulation of NPC differentiation during mouse embryonic brain development.
TRIM32 belongs to the TRIM-NHL family and it has been involved in NPCs' regulation of differentiation and self-renewal during mouse embryonic brain development.
Indeed, it has been shown that Top2b controls the expression of many developmentally regulated genes (e.g. Reln, Dab1, Epha gene family) during mouse embryonic brain development (Lyu et al., 2006), as well as gene activation in rat cerebellar granule cells (Tsutsui et al., 2001a; Sano et al., 2008).
In newborn mice where brain development is in a critical period, exposure to persistent organochlorines, such as PCBs, has been shown to cause severe, sometimes irreversible, brain disruption (Eriksson 1997; Eriksson et al. 2002).
Contribution of maternal oxygenic state to the effects of chronic postnatal hypoxia on mouse body and brain development.
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