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We collected the mouse body weights at indicated time for 60 days.
VLP H1 and VLP H2 inhibited tumor growth (A), reduced mouse weight (B), and tumor volumes (C) but did not decrease mouse body weights (D).
Interestingly, VLP H1 and VLP H2 did not decrease mouse body weights (Figure 4D) - a result consistent with the notion that VLP H1 and VLP H2 preferably target tumor cells and thus exhibited little toxicity to the animals.
Mouse body weights and tumor sizes were measured twice a week.
We monitored the mouse body weights twice weekly in order to detect signs of toxicity.
Individual mouse body weights were measured twice weekly.
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Tumor growth and mouse body weight were assessed twice weekly.
(DOC 34 KB) 13550_2013_185_MOESM3_ESM.doc Additional file 3: Figure S3: Mouse body weight changes after treatment.
The results showed that irradiation of mouse brain with 2 Gy of 12C6+ ion or 60Co γ-ray significantly diminished mouse body weight and level of serum GH.
13550_2013_185_MOESM1_ESM.doc Additional file 1: Figure S1: Mouse body weight change after treatment with RIT alone or in combination with chemotherapy.
Animals were treated with analgesics (Temgesic® 0.1 mg/kg, mouse body weight 23.2 ± 1.9 g) and anaesthetised by isoflurane inhalation (3%, 200 mL/min).
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