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Also for these experiments mice were kept in a supine position using the whole mouse body coil.
Again, for these experiments mice were kept in a supine position using the whole mouse body coil.
MRI analyses were performed in a whole mouse body coil using a T2-TSE (turbo spin echo) sequence.
Animals were scanned in 7 T small animal MRI (ClinScan, 7.0 T, 290 mT/m gradient strength) with a whole mouse body coil (Bruker, Ettlingen, Germany).
The MR and PET imaging studies were performed on a 1.0 T MR scanner (Aspect Imaging, Shoham, Israel) using a 35 mm mouse body coil, and a Siemens Inveon Multimodality PET/CT system (Siemens Medical Solutions Inc., Knoxville, TN, USA), respectively.
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Scans were performed on a 3T GE Excite MR750 system using a custom-built high-performance gradient insert with an inner diameter of 17.5 cm, maximum gradient strength of 500 mT/m and peak slew rate of 3,000 T/m/s, and a custom solenoidal whole-mouse body RF coil 4 cm in length and 3 cm in diameter.
The animal holder with the mouse body was mounted in the scanner equipped with a volume coil of 40 mm inner diameter.
The whole body coil is a volume coil that allows the imaging of the whole mouse without inducing any inhomogeneities of the signal.
No dedicated RF coils were positioned on the patient to perform body coil imaging only.
Open image in new window Fig. 4 Body coil vs array coil.
MR hydrography was performed using a SENSE body coil.
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