Sentence examples for mouse bladder resulted from inspiring English sources
The simultaneous deletion of Lkb1 and Pten in the mouse bladder resulted in diffusely hyperplasic atypical urothelium with papillary growths and the tumours were histologically similar to human neoplasms: by day 100 resembled a low grade papillary urothelial carcinoma and turned into high grade by day 125 [6125
Chronic BCG administration into the mouse urinary bladder resulted in pronounced inflammation accompanied by increased density of PGP9.5, TRPV1, SP, and CGRP nerves.
Image analysis of nerve density indicates that single or repeated challenge of mouse bladders with VEGF resulted in a significant increase in ChAT density in the urothelium, lamina propria, and detrusor smooth muscle.
Finally, instillation of VEGF121 or VEGF165 into the mouse bladder recapitulated the effects of BCG and resulted in a significant inflammation and increase in nerve density.
Although obtained with a particular model of mouse bladder tumour, we show here that our results are relevant to human bladder cancers.
In order to extend our previous results obtained with the mouse bladder [ 27], we also tested the presence of PA receptors in the J82 human urothelial cancer cell line.
Even though there were reports showing UPEC internalization by mouse bladder superficial epithelial cells, this was considered a result of phagocytosis by the bladder epithelium [12].
Additional results supported the hypothesis that the mouse bladder urothelium actively internalizes VEGF [ 31].
These results indicate that, at least in the mouse bladder, the instillation of 10 μM PAR4-AP or 100 μM PAR1-AP induces a strong inflammatory reaction characterized by the highest number of PMNs infiltrating the bladder.
Fig. 2 Functionalized mesoporous silica nanoparticles (MSN) are taken up by mouse bladder cancer cells.
Care should be taken to express the mouse bladder to avoid additional fluid in the RF field (bladder cannulation should be considered for long-term imaging protocols).
