Sentence examples for mouse bladder leads from inspiring English sources

We have previously shown that repeated BCG instillation in the mouse bladder leads to a strong cytokine response, including a significant increase in the production of IFN-γ and IL-17 proteins and their mRNAs [ 8].

mTOR hyperactivation in the mouse bladder led to a combination of EMT and abnormal proliferation.

Indeed, expressing mutant H-Ras within the mouse bladder does not lead to tumour formation, unless this is expressed at high levels.

A recent study concluded that inactivation of RB, in combination with either PTEN or p53 inactivation, in mouse bladder did not lead to a discernible phenotype (Puzio-Kuter et al., 2009).

We conclude that altered mTOR leads to EMT and tumorigenesis in the mouse bladder.

Fig. 2 Functionalized mesoporous silica nanoparticles (MSN) are taken up by mouse bladder cancer cells.

Care should be taken to express the mouse bladder to avoid additional fluid in the RF field (bladder cannulation should be considered for long-term imaging protocols).

Murine bladder cancer cells (MB49) were found to take up the MSN in vitro; in the mouse bladder, the MSN were taken up preferentially by tumor cells more readily than healthy bladder epithelium.

To understand the basis of bladder-associated pain, we next examined nerve fibers in the mouse bladder.

Combined deletion of Lkb1 and Pten led to a significant increase in levels of phosphorylated mTORS2448 and S6 ribosomal proteinS240/244 according to western blot (Fig. 1, B). Immunohistochemical staining showed that the increase in mTORS2448 and pS6S40/244 ribosomal protein (Fig. 4) occurred only in the epithelial layer of the mouse bladder of Lkb1/Pten-deficient mice.

Treatment with intravesical PAR1, PAR2 and PAR4 agonists induced inflammation in the mouse bladder [21].