Sentence examples for mouse asthma model from inspiring English sources

Oh, S. W. et al. Tryptase inhibition blocks airway inflammation in a mouse asthma model.

Furthermore, Id3 T cells showed greater differentiation into the T(H 17 subset of helper T cells in vitro and in a mouse asthma model.

McSorley et al. found that HES products inhibit the allergic reaction in the ovalbumin (OVA -induced mOVA -inducedmouse by suppressing the releasthma IL-33 and inhibiting the activation of ILC2s (modelley et al., 2014; McSorley et al., 2015).

The mouse asthma model was established as previously described [ 25] with some modifications.

Our preliminary data shows that activin A immunolocalization in airway epithelium is decreased in asthmatics (Fig. 1), akin to the situation in the mouse asthma model [ 18].

To conduct the study, human lung specimens and peripheral blood mononuclear cells (PBMCs) and a HDM-based mouse asthma model were used.

In mouse asthma models that use ovalbumin (Kim et al., 2012), house dust mite (HDM Wilhelmlm et al., 2011; Halim et al., 2012a; Klein Wolterink et al., 2012), papain (Halim et al., 2012a), and fungal allergens, ILC2s uniformly increase in number and are the major source of IL-5 or/and IL-13, especially in the early phases of the disease.

In guinea pig and mouse asthma models, DAS181 does not cause airway hyperreactivity (unpublished data).

Some researchers have demonstrated that synthetic TLR7 ligands can inhibit Th2 responses, airway remodeling and attenuate airway inflammation in mouse asthma models [19] [21].

Here, we will review how research utilizing mouse asthma models has generated clinically relevant findings regarding the pathogenesis of severe asthma and has revealed targets to exploit in the development of new treatments.

21 Administration of exogenous PD1 to mouse models of inflammation protects tissues from inflammatory damage, expediting phagocytic resolution of acute peritonitis and retinal injury models, attenuating inflammation and airway hyper-responsiveness in mouse asthma models, while mouse eosinophils contribute to the resolution of acute peritonitis in a 12/15-LOX-dependent 12/15-LOX-dependent 12/15-LOX-dependent