Kim Jee-woon is dealing not just with the cat-and-mouse aspect of the story, but the moral element as well: that, even as Kim tries to turn Kyung-chul's existence into living hell, he is becoming a monster himself.
In mice, aspects of prion disease susceptibility can be modelled by examining the incubation period following experimental inoculation.
In mice, aspects of prion disease susceptibility can be modelled using incubation time as a quantitative trait.
Many findings are common between flies and mice, other aspects have been studied more in one organism than the other and there are also aspects that are unique to either organism.
Upon examination of the results from this and previous sociability studies of Fmr1 knockout mice, two aspects stand out, (i) the limited magnitude, and (ii) the variability, in reported social behavior differences between Fmr1 knockout and wild-type mice.
Although we anticipated enhanced angiogenesis and tumor growth in Cstc−/− mice, several aspects of our results remain unexplained, and more studies are required for further understanding of the role of cathepsins in tumorigenesis.
In the heparanase-overexpressing mice, all aspects of immune cell recruitment and activation were significantly attenuated in both inflammation models, as was amyloid dispersion.
Previous studies have shown that major phenotypic deficits arising from MeCP2-deficiency may be reversible, as the delayed reactivation of the Mecp2 gene in Mecp2-deficient mice improved aspects of their Rett-like phenotype.
MS designed the experiment, performed all the mouse-related aspects of the study (surgeries, chronic stress exposure), collected the frontal cortex tissue punches, isolated the RNA, generated the cDNA, performed the qPCR on GABA-related genes, analyzed the data, and wrote the manuscript.
The phenotypes of Prokr2 and Prok2 knockout mice model aspects of human Kallman syndrome (KS), a partially penetrant genetic disease that causes OB deformity and consequently anosomia and hypogonadism with associated sterility and failure to reach puberty (Ng et al., 2005; Matsumoto et al., 2006).
Several of these mouse models exhibit aspects of HCV-related liver disease.
