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Mouse arthritis experiments are presented as mean ± SEM.
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Analysis of the frequency of CII-specific T cells by the end of the arthritis experiments showed that the B22a1-CD4+ B22a1-CD4+ depleTed micellsd expanded compared winh nontreatedepletedl mice (P = 0.038).
AB carried out the breeding of mice, the arthritis evolution experiments and joint isolation.
J.J.L. provided mice and helped design the mouse experiments.
For the serum transfer-induced arthritis (STIA) experiments, C57BL/6 mice were injected intraperitoneally with 100 µl of K/BxN serum in 200 µl PBS.
This is based primarily on our laboratory studies related to collagen induced arthritis (CIA) experiments involving rats and mice, where we observed a delay in the onset of arthritis in animals that were given Perna orally (manuscript in preparation).
Indeed, knockout mouse experiments revealed that the absence of MMP-9, but not of MMP-2, reduces arthritis progression [ 39].
contributed to humanized mouse experiments.
The mouse experiments were encouraging.
The mouse experiments were a run-up to monkey experiments.
T.K. co-designed the mouse experiments.
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