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The lab team called it a mouse, and found it pointed more efficiently than light-pens or knee-nudged devices.
To better understand the hypothalamic contribution of estrogen signaling, we first characterized some behavioral aspects of the whole-body ERα knockout mouse, and found that they had decreased homecage locomotor activity and voluntary wheel running activity, increased body weight, and changes in fat distribution to favor development of the metabolic syndrome.
We also counted the number of peritoneal cells extracted from each mouse and found that a 2 day diclofenac treatment yielded a 3 fold increase in cells from tumor-free mice.
In our model, we used two doses of 100 µg of the anti-4-1BB antibody per mouse and found that this was sufficient to allow 80% mouse survival when combined with adoptive T cell transfer.
To examine the nature of the immune response to HuD, we have studied HuD-specific CD8 T cells in the mouse, and found that there is normally robust tolerance to this neuronal protein in vivo.
To make sure that our results are not influenced by different ENSEMBL versions, we also performed our analyses on two previous versions (v39 and v41) for both human and mouse and found that the results are very similar to results based on version 46.
Similar(41)
Schools are to be given advice on how to disable a glitch that allows pupils sitting online spelling tests to right-click their mouse and find the answer.
But Hood says she feels a new sense of certainty that someday, someone will click on a mouse and find a connection.
The investigators tested rycals in mice and found that they could prevent heart failure and arrhythmias in the animals.
He and Dr. Benezra transplanted bone marrow from normal mice into Dr. Benezra's vessel-defective mice, and found that the mice would then support tumors.
One study assessed long-term behavioral outcomes in mice and found no effect.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com