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Exact(20)
Combined, these results are more consistent with the idea that endogenous ligands initiate MuSK activation in mouse and fish embryos.
Among the clock genes identified from the Notch pathway, the hairy related or homologous genes in mouse and fish, namely Hes and her, also cycle [5] [9].
Localized ONL expression is consistent with previous work in mouse and fish highlighting the importance of local TH levels, developmental timing of TH exposure, and especially TRβ expression in cone opsin regulation and photoreceptor maturation [14], [42] [44], [46], [48], [49].
Inhibition of miRNA biogenesis has resulted in developmental arrest in mouse and fish [ 19- 21].
Interestingly, it has been reported that PI3K signaling is essential for angiogenesis in mouse and fish development.
This similarity of results achieved in mouse and fish models reinforces the validity of exploiting the latter to study NAFLD.
Similar(40)
Consistent with previous years, 97% of the scientific procedures last year involved rats, birds, mice and fish.
Where there was an increase was in mice and fish – the latter up a whopping 23 per cent.
But we are also related, albeit more and more distantly, to mice and fish and beetles and mushrooms and oak trees and so on, outwards to the humblest bacterium.
Today there are more experiments recorded, but the animals used are mostly mice and fish and the procedures are considerably less severe.
Judy MacArthur Clark, head of the Home Office's Animals in Science Regulation Unit, said that the 8% overall rise might sound dramatic: "But we know, within that, there's been a significant increase in the breeding of genetically altered animals and this [is] primarily mice and fish.
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