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Our results imply that masting also affects the dynamics of the yellow-necked mouse and, consequently, the multiannual dynamics of LCMV in this host species.
Human tumor antigens such as Her2/ neu are not present in the mouse and, consequently, are not subject to immune regulation as would be expected in the patient with breast cancer.
Recently, it was found that the tempo of the segmentation clock is accelerated in snake embryos, "ticking" around four times faster relative to growth rate than in shorter-bodied animals like chick and mouse and consequently generating a large number of somites [ 80].
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Altogether, these data provide indirect evidence that iNKT cells are not involved in controlling the induction of CTL tolerance in TRAMP mice and, consequently, the anti-tumor effector T cell response.
The beneficial HDL-cholesterol was markedly elevated in Lean mice and consequently the Lean mice showed significantly lower ratios of atherogenic non-HDL-cholesterol versus total plasma cholesterol.
Removal of the endothelium did not augment contraction in aortas from +/ Col3a1▵ mice and, consequently, contractile responses were similar in denuded aortas from +/+ and +/ Col3a1▵ mice.
PKR is activated in tissues of obese mice and, consequently, can directly or indirectly (through JNK activation) induce negative phosphorylation of IRS1 as well as activation of IKK.
Our findings show that MPO activity is highly activated in HOCl-treated mice, and consequently, PTU administration decreased its activity in the lungs.
These mice appear to be healthier than the other transgenic mice and consequently we have been able to maintain this line probably due to lower G0S2 levels than other transgenic mice.
Furthermore, since the generation time in mice is shorter than in humans, there will be more generations that are subject to selective pressures for mice and consequently, more duplicates retained in the mouse genome.
Our data provides compelling evidence to show that increased ATGL and HSL activity in adipose tissue causes changes in FA homeostasis in serum and liver of MCD-fed mice and consequently leads to hepatic steatosis and lipotoxicity.
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