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The mouse AM cell line, MH-S (American Type Culture Collection, Manassas, VA), was used as a model system for studying the direct effects of EtOH exposure in vitro.
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Dittmer, F. et al. Alternative mechanisms for trafficking of lysosomal enzymes in mannose 6-phospahte receptor-deficient mice are cell type-specific.
defective migration to inflamed tissues in FtDKO mice is T cell intrinsic [25].
Production of autoAbs in these mice was T cell-dependent.
"We saw that most metastases in mice are caused by cell clusters," Padmanaban says.
Four mice were injected per cell line.
The accelerated satellite cell proliferation observed in RNF13-/ mice is mainly non-cell autonomous.
Open image in new window Figure 3 Accelerated satellite cell activation and proliferation inRNF13 -/- mice is mainly non-cell autonomous.
The paper also noted that, while the original cells from Wakayama's mice were female, the STAP cells were male, "a clear inconsistency".
Mammary pads of female BALB/c mice were injected with 4T1 cells.
Such seemingly normal mice are genetic mosaics; some cells in their bodies are from one parental lineage and some from another.
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CEO of Professional Science Editing for Scientists @ prosciediting.com