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When atopy and exposure were considered together, 53% of those with more than 4 positive PST responses and allergen levels above the median had a positive PST response to mouse allergen compared with 22% of those with more than 4 positive PST responses and allergen levels below the median (P <.0001).
However, restricting the analysis to low-income, urban homes in the NSLAH, the prevalence and distributions of mouse allergen compared well with previous findings from inner-city populations.
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Mice that had received active treatment with either Bet v 1.0101, FPH, or FPH4 showed significantly reduced serum IgE to the WT allergens compared with mice pre-treated with PBS (Fig. 6b).
There was a trend toward a greater reduction in mouse allergen levels in the remediated group compared with control at EV3 and a similar trend toward greater β-glucan reduction in the control group compared with remediation at EV3 (data not shown).
The highest levels of mouse allergen were found in kitchens, followed by bedrooms and then living rooms.
Conclusions: Mouse allergen may be an important indoor allergen in inner-city children with asthma, with exposure and atopy contributing to mouse sensitization.
Little is known about exposure to mouse allergen (Mus m 1) and allergic rhinitis (AR).
Data were analyzed to relate mouse allergen exposure and other risk factors to mouse sensitization and asthma morbidity.
In a study involving eight urban areas, scientists at Johns Hopkins University discovered that 95percentt of tested homes had at least one room containing mouse allergen -- substances that cause allergic reactions, like mouse urine or dander.
The relationship among mouse allergen exposure, sensitization, and any measures of asthma morbidity was not statistically significant.
The allergen assays included cockroach allergen Bla g 1, dust mite allergens Der f 1 and Der p 1, cat allergen Fel d 1, dog allergen Can f 1, mouse allergen Mus m 1, and allergens of the fungus Alternaria alternata.
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