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Obviously, the organism was cleared to a large extent or changed to a viable-but-non-culturable state after manifestation of infection, since all four goats shed MAP until at least 10 wpi, all mounted a specific IFN-γ response, and tissue lesions were found in three of them.
These results demonstrated that a broad spectrum of cytokines was produced in the in vitro-generated T-cell response (LJ Mu et al, unpublished; Kyte et al, 2005) All of the patients who mounted a specific T-cell response also developed a component of MLR reactive cells recognising DCn.
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The IRS maintains that it is not mounting a specific attack on S corps, which are not audited as often as C corps.
We also found that mice mount a specific IgG response against three proteins (40, 47, and 56 kDa) regardless of the strain used, suggesting that these may be immuno-dominant antigens.
The system responds by mounting a specific immune response from the beginning of exposure.
Taking into account that integration-deficient lentiviral vectors could allow efficient expression of a foreign gene in professional antigen-presenting cells, we next explored their abilities to mount a specific immune response.
While it is known that amphibian antimicrobial peptides (AMPs) correlate with species survival against Bd [10], [11], it is not known if amphibians mount a specific response against Bd, or to what extent any host response is temperature-dependent.
Other research has shown that Xenopus is capable of mounting a specific immune response to Ranavirus under laboratory conditions [32]; it is possible that this is also occurring in the Rv+ populations in our study.
However, the diminished protection observed in SCID mice compared to BALB/c mice could be explained by the deficiency of B and T-cells in these mice and their inability to mount a specific response to the bacterial challenge following depletion of the passively transferred antibodies.
Ross et al. (1995) also found that contaminant-fed seals were less able to mount a specific immune response to oval-bumin.
In contrast to most healthy persons, patients with pre-malignant high-grade cervical intraepithelial neoplasia (CIN) and cervical cancer patients fail to mount a specific immune response or displayed an impaired response against the early antigens of HPV16.
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