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Design: Automated decomposition-enhanced spike-triggered averaging was used to characterize motor unit size and firing rate in the dominant vastus medialis during maintained contractions at 10%and30%0% of maxima voluntary contraction (MVC).
A second measure is the ratio of motor unit size (mean SMUP area) to force generation, which estimates the average motor unit size per Newton force (N) produced by the knee extensors.
A nonlinear relationship was found between muscle force generation and motor unit size with an explained variance of 0.67.
The effect of CNTF on nerve development suggests that CNTF genotype may be associated with force production via its influence on motor unit size and firing patterns.
In contrast, G/G subjects show a different pattern with little difference in motor unit size (SMUP area) per unit force at low and high force levels.
The primary measures resulting from this approach are an estimate of individual motor unit size from the SMUP and individual motor unit mean firing rates (mFR).
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To better demonstrate the differences in motor unit sizes between G/A and G/G at forces less than and greater than 200 N, density distributions were plotted for SMUP and MUmV.
Strength of muscle contraction is dependent on the number of active motor units, their size, the rate of stimulation of the motor units, and the type of muscle fibres.
This provides an estimate of the force capabilities of the motor units per unit size.
No abnormal spontaneous activity was seen, and motor unit potentials had normal size, configuration and recruitment, with low firing frequency consistent with the level of anesthesia.
The two groups used motor units with different size and activation characteristics with increasing force generation.
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