Sentence examples for motor neurons compared from inspiring English sources

14 Markedly elevated CSF NfL levels in ALS may be explained by the higher content of axonal proteins in motor neurons compared to other neuronal populations.

For example, there appear to be less defined D169G puncta in primary motor neurons compared with other variants, suggesting that the association with neuronal RNA granules is dependent on a fully functional RRM1 domain.

Exposure to rotenone accelerated the decline in TMRM fluorescence in AR100 motor neurons compared to control, indicative of an abnormally enhanced depolarisation of ΔΨM.

Patient stem cell clones produced a similar number of motor neurons compared to controls, with or without androgen treatment.

We found that 178 genes were upregulated, whilst 287 genes were significantly downregulated in AR100 motor neurons compared with WT cultures (Supplementary Information, Fig. S1A C and Tables S1, S2).

LA-PCR analysis of isolated genomic DNA showed significantly delayed repair of DNA strand breaks in both R521H and P525L mutant motor neurons compared to the control WT cells (Fig. 5g, h).

Of these, only 2 were statistically up-regulated in SMAr motor neuron compared to WTr (Fig.  9a).

Motor neuron sensitivity correlates with the NO-dependent formation of 3NY, which is significantly more pronounced in motor neurons when compared with oligodendrocytes, suggesting peroxynitrite as the toxic molecule.

Overall, this EphB1 activated phenotype is characterised by diminished Cebpd and increased Trim30a expression, and induced a significantly less cleaved-caspase3 IR in motor neurons when compared to the IL-6-induced astrocyte phenotype, suggesting a protective role.

Pretreatment with NF-κB inhibitor significantly reduced NF-κB expression and the number of intact motor neurons when compared to the control group.

To investigate whether increasing NR3B expression may contribute to the loss in late development of activity-dependent dendritic reorganization in the spinal cord, we over-expressed NR3B in cultured rat spinal motor neurons, and compared its effects on dendrite morphology with the effects of pharmacological blockade of NMDA receptors.