Sentence examples for motor neuron score from inspiring English sources

The mean baseline upper motor neuron score for all patients was 9 ± 4 (range 0 15).

Whole-brain voxel-wise VBM analysis did not yield any significant correlations with the upper motor neuron score.

Clinical and cognitive scores where available [upper motor neuron score, ALSFRS-R total score and subscores, and progression rate (VBM: n = 60, TBSS: n = 43), and ACE total (VBM: n = 32, TBSS: n = 22) and subscores (VBM: n = 45, TBSS: n = 35)] were then regressed with the preprocessed VBM and TBSS images (for the respective T0 MRI scans) (Supplementary Fig. 1).

Although the sensitivity, limitations and potential confounds of DTI are well recognized, the additional observation of a lack of change for most patients in their clinical upper motor neuron score over time (not previously reported to our knowledge) may have implications for the sequence of pathological change in ALS, and understanding the variable regional spread of symptoms.

There was notably limited variability in individual patient upper motor neuron scores over time (Supplementary Fig. 2A).

In contrast there was limited white matter pathology progression, in keeping with a previously unrecognized limited change in individual clinical upper motor neuron scores, despite advancing disability.

Third, this core white matter DTI signature does not seem to significantly evolve, in keeping with the novel observation that individual clinical upper motor neuron scores show rather limited variability as disability proceeds.

7 Specifically, in ALS, a strong DTI white matter signature involving the corticospinal tracts (CSTs) and motor fibers in the corpus callosum (CC) has been consistently identified at group level, 8, 9 and FA and RD measures in the CSTs were found to correlate with upper motor neuron (UMN) score and progression rate.

No statistically significant association between the reduction in cortical FMZ binding and revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) was demonstrated in sALS patients, whereas the upper motor neuron (UMN) score correlated with widespread and marked cortical decreases over the dominant hemisphere.

An upper motor neuron clinical burden score out of 15 comprised the number of pathologically brisk reflexes [extensor plantar responses (2), brisk facial and jaw jerks (3), biceps (2), supinator (2), triceps (2), finger (2), knee (2), and ankle reflexes] (Turner et al., 2004).

Second, the core cerebral white matter involvement, mainly involving the corticospinal tracts, is linked more strongly to clinical upper motor neuron involvement rather than disability score as measured by the ALSFRS-R.