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Motor neuron population model.
Interestingly, the dorsal spreading of Phox2a expression and putative motor neuron population was seen in the midbrain but not in the rhombomere 1.
The response of the circular muscle to inhibitory and excitatory motor neuron input was calculated as
In this study, we showed upregulation of the GluR2 subunit in resistant OM neurons, relative to the vulnerable lumbar motor neuron population.
So if motor neurons have a preference for antisense transcription of the C9ORF72 expansion then the motor neuron population will express higher levels of antisense RNA derived foci and DPRs, but not necessarily within the same individual cells.
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For instance, ALS and SMA are both motor neuron diseases, but they affect different motor neuron populations.
This resampling procedure was performed for both control and lesioned motor neuron populations, and the difference in connection strength found.
Vulnerable and less vulnerable motor neuron populations were isolated from both SMA and wild-type control mice.
The epitope recognized by C4F6 is not known, but this antibody binds to soluble misfolded SOD1 in disease-affected motor neuron populations in ALS patient spinal cord.
It is possible that this basal higher level of cellular stress primes selective motor neuron populations to cope better with the additional stresses when Smn levels are reduced.
Sharp electrode recordings from the motor neuron cell body of postnatal (6- to 10-days old) presymptomatic SOD1 G85R mice have revealed hyperexcitability in motor neuron populations in the spinal cord (Bories et al., 2007).
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motor neuron phenotype
motor neuron lesion
motor neuron dysfunction
motor neuron damage
motor neuron disorder
motor neuron specification
motor neuron degeneration
motor neuron protection
motor neuron vulnerability
motor neuron number
motor neuron survival
motor neuron pool
motor neuron soma
motor neuron circuitry
motor neuron stress
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