Sentence examples for motor neuron development from inspiring English sources
We found co-localization between TAF9B and OLIG2 at both the TAF9B distal peaks and at the TAF9B TSS peaks, suggesting that TAF9B and OLIG2 act in concert at a subset of neuronal genes to regulate gene expression during motor neuron development.
Mutant PHP tau: altered motor neuron development.
Genes involved in neuromast and motor neuron development were significantly enriched, agreeing with our previous results showing motor neuron and neuromast damage in the embryos.
These results indicate that the cranial motor neuron development is very vulnerable to nestin defects.
Thus, the presence of the ju89 tba-1 allele was sufficient to alter motor neuron development and function.
While studies in SMA mice have not revealed axon guidance or elongation defects in vivo, the hypothesis that the localization and local translation of ß-actin is important for normal motor neuron development cannot be ruled out.
Approximately 13 h AEL, development of ventral NMJs begins when motor neuron growth cone filopodia contact the target muscles.
Extrapolating the data presented in the current study, demonstrating a requirement for heparanase 2 for correct peripheral motor neuron functional development in the trunk region, we propose a similar requirement for heparanase 2 in the development of other peripheral motor nerves, including those of the human face and viscera.
Enhancing Met levels in neurons does not affect either motor neuron (MN) development or maintenance.
When this signalling system is abnormally upregulated (Fig. 8B), motor neuron functional development is perturbed resulting in skeletal muscle motility defects.
In addition, we demonstrate that knockdown of both Tardbp and Tardbpl-FL leads to severe defects in motor neuronal development, therefore establishing a vital role for Tardbp in motor neuron and axon development.
