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Although 729 of these transcripts are also scored as "present" in the unc-4 GFP unc-4 GFPon dataset, we attribute their detection to high expression in the smotorfractioneuron%) of non-GFP cells contaminating this preparation (see above).
The strong representation of ~80% of genes known to be expressed in I5, SAB, and DA motor neurons in the unc-4 GFP unc-4 GFPon dataset indicates that other previously uncharacterized transcripts in this list are also likely to be expressed in these cells in vivo.
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Human endogenous retrovirus-K contributes to motor neuron disease.
"You could make neurons from induced pluripotent stem cells taken from patients with Parkinson's or motor neuron disease.
Diane Pretty, 42, suffers from motor neuron disease and is paralyzed from the neck down.
MN, motor neuron.
Survival motor neuron.
Lower motor neuron.
Mutant PHP tau: altered motor neuron development.
(A) Schematic overview of motor neuron differentiation from iPSCs.
CSM involves either the upper motor neuron or lower motor neuron (LMN) in the cervical spine.
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