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DSPN is characterized by progressive distal and symmetrical sensory and autonomic nerve damage with eventual motor nerve involvement (1).
Diabetic sensorimotor polyneuropathy (DSPN) is a length-dependent, symmetrical neuropathy with initial involvement of sensory and autonomic nerve fibers (NFs), followed by motor nerve involvement (1).
50% (4 patients) had schwannoma affecting mixed nerves, 37.5% (3 patients) had pure sensory nerve involvement, and 12.5% (1 patient) had pure motor nerve involvement.
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Thus, in the context of WNV infection, electrodiagnostic studies previously interpreted as motor axonal polyneuropathy or motor axonopathy without sensory nerve involvement (4 – 6 ) are more suggestive of anterior horn cell loss than of Guillain-Barré syndrome.
12.5% (1 patient) had involvement of motor nerve, 37.5% (3 patients) had involvement of sensory nerve, and 50% (4 patients) had involvement of mixed nerve.
Neurophysiologic examinations excluded a peripheral sensory motor neuropathy and other cranial nerve involvement.
Although herpes zoster typically resolves within 3 5 weeks, certain complications may arise: Secondary bacterial infection Motor involvement, including weakness especially in "motor herpes zoster" Eye involvement: trigeminal nerve involvement (as seen in herpes ophthalmicus) should be treated early and aggressively as it may lead to blindness.
Our results give some support to this hypothesis as we observe that the prevalence of MRI findings of decreased disc water and height and protrusion, and of the physical examination findings of disturbed sensibility to pain and disturbed motor function and pain drawing findings of nerve involvement were in the same quartile (between 77 and 95%).
Regarding the clinical presentation, we found that all patients (100%) had both motor and sensory symptoms, while 54.2% had facial nerve involvement, 16.7% had autonomic symptoms, and 16.7% needed MV.
These include forms with only patchy sensory loss, mild electrical motor nerve abnormalities and predominant small fibre or isolated lower limb involvement.
In the study population, sensory neuronopathy showed a common clinical and electrophysiological pattern that was independent of the underlying cause, including unusual forms with only patchy sensory loss, mild electrical motor nerve abnormalities and predominant small fibre or isolated lower limb involvement.
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