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However, 4 out of 6 male subjects exhibited motor learning, compared to only 1 out of 6 females.
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In previous self-controlled feedback studies, it was observed that participants who could control their own feedback schedules usually use a strategy of choosing feedback after successful trials, and present superior motor learning when compared with participants who were not allowed to choose.
We assessed online motor learning by comparing behavioural measures (accuracy and error magnitude) and the extent of spatial activation in specific brain regions of interest (ROIs) using fMRI pre- and post-training.
GFAP-ApoE4 mice exhibited impaired motor learning and diminished strength compared to the GFAP-ApoE3 mice.
However, to assess the motor learning and behavior we compared the Ms2Yah mice with controls, using the rotarod and treadmill paradigms.
However, when analysed individually, we found that 4 out of 6 males and 1 out of 6 females showed significant difference between two categories of motor pattern (two sample t test: bottom row of Table 1).> -wrap-foot> In case of analysis for motor learning, the RTs were compared between the test sequences with and without motor pattern consistent to the baseline sequence.
Here, we used ten different VOR motor learning paradigms to directly compare the effect of disrupted P/Q signaling on the regulation of VOR phase versus gain by motor learning.
In a recent report, PTPN3-deficient mice were also shown to have impaired memory function and motor learning, albeit that significant differences compared to controls were detected only in females [34].
The findings provide support for the proposition of different motor learning principles in older adults compared to younger adults.
Our findings provide support for the proposition of different motor learning principles in older adults compared to younger adults, because the older individuals were not taking an advantage of adopting an external focus of attention.
We compared two motor learning paradigms that elicited equally robust putative error signals in the same climbing fibers: learned increases and decreases in the gain of the vestibulo-ocular reflex (VOR).
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