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Finally, this CD8+ T cell-mediated, perforin-dependent loss of motor function did not occur following adoptive transfer of SCILs into demyelinated β2microglobulin-deficient B10Q host mice (P<0.001 β2m−/− hosts vs perforin-deficient hosts) (Figure 6G).
Dlx-CKO pre-weaning motor function did not differ from littermate controls.
The effects on motor function did not reach statistical significance but all patients already had a stable motor component and there was no requirement for additional therapy.
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The reconstruction of motor function does not necessarily reverse a putatively maladaptive cortical representation, which was expected from the naive hypothesis.
Motor function returns to preinjury levels by 7 days thus ensuring that altered motor function does not alter performance on the hierarchy of behavioral tasks (Table 1).
If motor function does not recover, tendon transfer will restore the function satisfactorily.
Thus, while CD clearly ablates motility, it would seem that curtailing motor function does not change all gross parameters of ookinete motion.
16 The distribution of cerebral palsy subtypes and gross or fine motor functions did not differ when comparing the characteristics of the children with cerebral palsy between habilitation centres with nearly complete recording of cases (>90% of cases) and habilitation centres with low participation (<90% of cases).
Our tests of sensory-motor function did not reveal deficits (Online Resources: Methods) and thus excluded the possibility that trapping behavior was due to the secondary effects of the transgenic intervention.
Thus, deficient motor functions do not seem to be a significant predictor for predictability of response sequences in the task at hand.
In contrast, the ALS motor score, which provides a more holistic view of motor function [11], did not vary significantly between groups at any time beyond age 12 wk.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com