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Mice were tested for motor coordination using a balance beam [21].
We also assessed motor coordination using a Rotarod and found that the ability to stay on the Rotarod decreased significantly with age.
The NCF assessment comprised 3 domains: 1) memory using the revised Hopkins Verbal Learning Test, 2) executive function using the Controlled Oral Word Association and Trailmaking Test B, and 3) fine motor coordination using the pegboard dominant and nondominant hand tests.
Given the benefitial effects of dexamethasone observed in the cerebellum (Supplementary Fig 1B) and because ataxia is evident in ASMko mice at 4 months of age (Horinouchi et al, 1995; Macauley et al, 2008), we investigated the impact of dexamethasone treatment in ASMko female motor coordination using the vertical pole test (Ogawa et al, 1985).
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Motor coordination used as a rough estimate of neurological involvement was tested using a Rotarod device (Fig. 4).
Also, the motor coordination trained using plyometrics (jumping) is vastly different to the patterns used during the maximal peak power test, with a high rowing resistance.
In the current work we examined the anxiolytic effects of methanolic extract of Urtica urens, using the light/dark test and the hole board, and to examine motor coordination we used Rota rod test.
Specifically, a hardware model of the olivo-cerebellar dynamics controlling vertebrate motor coordination is used to control movement in an underwater robotic vehicle.
The time spent in both compartments was recorded for 10 min. To test for motor coordination we used the RotaRod from Med-Associates (St, Albans, Vermont).
Therefore, we assessed coordination using rotarod testing and gait analysis using a treadmill system to determine whether mice lacking Lrsam1 had motor impairment.
In addition, our finding of relatively good visual-motor coordination measured using "block design" or "object assembly" in CI subjects is consistent with one previous report [ 30].
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