Sentence examples for motor coordination defects from inspiring English sources

P-Rex2-deficient mice also exhibit mild motor coordination defects which worsen with age, particularly in females.

Such motor coordination defects depend mainly on a faulty cerebellar circuitry.

To our knowledge, only one study has examined these murine models of BLOC-1 deficiency for neurological abnormalities and reported motor coordination defects (Newell-Litwa et al., 2010).

P-Rex1 and P-Rex2 double knockout mice exhibit more severe motor coordination defects together with ataxia, abnormal posture, and gait [ 84].

However, 3-month-old Dpr1 fl/fl Nestin-Cre mice began to show motor coordination defl/fl Nestin-Crearod test, and they culmiceted in abeganal limb-clasping reflexes ato12 monthshowd, which is often associated with neurodegenerative diseases.

There are, however, conflicting reports describing the motor coordination defects in σ1R−/− mice that is detected by accelerating RT with a rate of 4 50 r.p.m. for 2.5 min.

To gain insights into the nature of the motor coordination defect, mice were examined using the "CatWalk" test.

The mice show retarded growth and severe motor coordination defect by week 5 and cerebellar atrophy by week 13.

Dpr1 ablation in the central nervous system results in motor coordination defect and accumulation of p62 and ubiquitinated proteins.

The GRP78 conditional knockout mice developed Purkinje cell degeneration by 4.5 week, associating with severe motor coordination defect by week 5 and cerebellar atrophy by week 13, thereby establishing the requirement of GRP78 for Purkinje cell survival and normal cerebellar function.

In spite of their small cerebella with foliation defects, miR-17∼92cKO; miR-106b∼25KO mice were asymptomatic with no evidence of gross neurological symptoms including motor coordination or balance defects measured on a Rotarod (negative data not shown).