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Other supporting numerical studies are made to examine the sensitivity of the solution and boundary motion to changes in diffusion and reaction rate for both linear and nonlinear reactions.
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In other ABC ATPases involved in membrane transport processes, such as the BtuCD vitamin transporter (Locher et al, 2002) the transmembrane subunit binds the ATPase domain at a sequence directly adjacent to the Q-loop, so as to connect ATP-driven motion to conformational changes in a partner protein.
The molecular motor myosin is proposed to bind to actin and swing its light-chain binding region through a large angle to produce an ∼10 nm step in motion coupled to changes in the nucleotide state at the active site.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com