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This work aims to evaluate the motion correction performance of these image-based methods on an occupancy study where the competitive binding can impose further challenges for conducting image registration on the PET images.
Data from eight healthy volunteers scanned with [11C]--PHNO pre- and post-administration of a range of doses of the D3 antagonist GSK618334 were used to compare the motion correction performance.
The motion of the model eye was calculated from SLO measurements with and without tracking to determine the motion correction performance.
The higher this value, the more similar the volumes are, indicating good motion correction performance, i.e. undistorted and consistent result volumes.
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Eddy-current correction and head motion correction were performed with fMRIB's Diffusion Toolbox 2.0.
Motion correction was performed, and the resulting images were subtracted from the baseline non-contrast image.
Respiratory motion correction improves the quantitative performance with the greatest benefit observed for patients of breathing type-2.
The influence of the motion correction process on the performance of the proposed CAD system is investigated primarily.
All volumes were scanned with a horizontal fast scan axis and motion correction was not performed.
As it can be observed from Fig. 7, the motion correction process offers a better performance for detecting breast lesions.
The performance of motion correction algorithms can therefore be evaluated by how close the structure as depicted in the volume is to the true structure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com