Several genes related to cell motility were upregulated in both the tibia and lung SRC tumors.
The results from this study indicate that after 20 minutes of OPP exposure, genes involved in anaerobic metabolism and swarming motility were upregulated.
Results from this study indicate that after 20 minutes of exposure to OPP, genes that have been linked to the exhibition of anaerobic respiration and swarming motility were upregulated.
Fascin, an actin-bundling protein involved in filopodial motility, is upregulated in several types of carcinomas; fascin upregulation is correlated with ER– breast cancer and a more aggressive clinical course (Arjonen et al, 2011).
Planar polar component of WNT pathway, involved in regulation of cell adhesion and motility, was upregulated in cornea only (table 5).
After 20 minutes of exposure to 0.82 mM OPP, genes involved in the exhibition of swarming motility and anaerobic respiration were upregulated.
Specifically, the pathways of energy generation, respiration, motility, and serine utilization were upregulated, whereas the pathways for iron uptake and utilization of proline, glutamate, aspartate, and lactate were down-regulated.
In contrast to the pathogenesis of P. aeruginosa in CF lung infection, the expression of genes for motility and flagellar biosynthesis were upregulated, allowing B. cenocepacia to maintain a potentially invasive phenotype characteristic of cepacia syndrome.
Our microarray analysis showed that gene families relating to cell motility, chemotaxis and cytoskeletal organisation were upregulated in the presence of high levels of NET1.
Multiple kinesin, myosin and dynein motors were upregulated, perhaps to compensate for the inhibition of vesicle motility characteristic of cells lacking NPC1 function [56], [57].
Compared to the pluripotent stem cell source, cytosolic AK1 and AK5 isoforms were upregulated, while mitochondrial AK2 and AK4 and cell motility-associated AK7 were downregulated in cardiomyocytes (Figure 1A).
