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Addition of hyaluronan, a nonsulfated glycosaminoglycan, to fresh and frozen thawed human semen results in substantial retention of motility over time.
For example, compounds #26, #37 and #38 had the most significant effect on Kremer testing which is broadly consistent, at least for compounds #37 and #38 with the positive effect on motility over time (Table I).
Previous reports have observed sporozoite motility in the dermis (Amino et al., 2006; Hellmann et al., 2011), but an in-depth analysis of their motility over time has not been performed.
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DOI: http://dx.doi.org/10.7554/eLife.07789.004 10.7554/eLiFigure89.005 Figure 1 figure supplement 1. Absolute number of sporozoites exhibiting different motility patterns over time.
These data suggest that sporozoite motility changes over time such that after an initial phase of maximal dispersal, sporozoites move in more constrained circular paths.
"People change over time.
Table II demonstrates that stimulation of total motility was maintained over time; however, progressive motility was not consistently affected using compounds #1 and #30.
The motility and displacement over time of the few filopodia that did form in GFP-LIMK1D460A-expressing GFP-LIMK1D460A-expressing GFP-LIMK1D460A-expressingof cellsol cells.
Sperm motility, which declines over time and is therefore not a reliable measure for shipped semen, was not included in the statistical analysis.
To further characterize mitochondrial movement, the motility of individual mitochondria over time was plotted in an x-y velocity graph.
Sporozoite motility is increasingly constrained over time and is not well described by a Brownian walk.
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