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To investigate the role of the cumulus cells and the cumulus matrix in affecting the penetrability, morphology, acrosome reaction, and motility of human spermatozoa penetrating the cumulus oophorus.
Since the seminal prostasomes are able to promote the forward motility of human spermatozoa, we conducted a study to determine whether PC-3 prostasomes exerted effects similar to those of seminal prostasomes on buffer-washed spermatozoa from normospermic semen samples.
In vitro studies of the initial attachment, spreading and motility of human bone mesenchymal stem cells have been carried out on bovine osteopontin (OPN) coated hydroxyapatite (HA) and gold (Au) model surfaces.
The initial attachment, spreading and motility of human mesenchymal stem cells show a larger cell area, a faster arrangement of vinculin in the basal cell membrane and more motile cells on the OPN coated HA surfaces as compared to the OPN coated Au surfaces and to the uncoated Au and HA surfaces.
Microarray and q PCR analysis showed RA treatment did inhibit the motility of human RPE cells by inhibition of metalloproteinases (MMP) 1, 2, 9, fibronectin-1, transforming growth factor beta, thrombospondin-1, tenascin C, most collagen, integrin, laminin molecules and along enhancing E-cadherin and MMP3 genes expression.
Vitamin A and its analogues have profound effects on the differentiation, morphology and motility of human keratinocytes in culture.
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The motilities of human spermatozoa cells from random high magnification fields (100x) of the sample were determined in duplicate using atomic force microscope.
We already demonstrated that p27 is able to inhibit the motility of several human cancer cell lines, including HT-1080 fibrosarcellscells (Figure 6) and [19] and U87MG [data not shown and Ref 20] in transwell migration assays.
Fermenticin was shown to significantly (P < 0.05) reduce motility of the human spermatozoa in a concentration-dependent manner.
Therefore, the purpose of this study was to clarify the effect of TGZ on the cell motility of a human ovarian cancer cell line.
All these bioactive lipids strongly enhance motility and adhesion of human RMS cells, and, more importantly, these metastatic-associated phenomena were observed at physiological concentrations of these lipids that naturally occur in biological fluids [25].
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