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Selumetinib treatment impaired the motility of both cell types in a dose-dependent manner, corresponding to the observed decreases in S405/418 phosphorylation (Figure 2B).
Overexpression of stathmin stimulates motility of both GN-11 neurons [ 15] and HT-1080 fibrosarcellscells [ 16, 17].
Calcium regulates invasion and motility of both these infective stages (Coppi et al., 2007; Siden-Kiamos et al., 2006).
The motility of both the paclitaxel- and the doxorubicin-selected variants were found to have further increased.
Thus, proposing a colectomy to patients with severe slow transit constipation, without having evaluated the motility of both ano-rectum and small bowel by manometry, should be avoided.
Figure 11 shows the motility of both MDA-MB-231 and MDA-MB-468 cells 6 hours after seeding the cells and Figure 12 after 20 hours.
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The dominant negative mutant EGFP-Rac1(T17N) did not alter the motility of mitochondria in both cell lines (Fig. 1K).
Our experiments confirmed that PACs decreased the swarming motility of P. aeruginosa, both in the distance moved and the complexity of the swarming pattern.
Additionally, CCN4, a protein capable of inhibiting invasion and motility of tumor cells both in vivo as well as in vitro, inhibits Rac activation [ 35], which is thought to be intimately involved in regulation of cytoskeletal organization [ 35].
The motility characteristics of both control and nanoselected spermatozoa were evaluated before and after nanoselection, followed by their use for double inseminations of six estrus synchronized gilts (2 doses/boar/gilt; 3 gilts /control or nanoselected).
The same concentration of BP7033Br ALK induced stronger motility inhibition of both cell lines (62 and 50%, respectively).
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