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Molecular control of actin organization is probably at the core of cell motility, and it is of importance that we gain an understanding of the mechanisms that underlie the regulation of actin dynamics so that we may appreciate how motility is regulated.
These results suggest that cell motility is regulated by the collagen gradient with a surface-density dependent manner.
Many studies have demonstrated that the development and maintenance of motility is regulated by a complex balance between kinase and phosphatase activities (Tash and Bracho [1994]; Porter and Sale [2000], King [2000]; Aparicio et al. [2007]).
Both microtubules and actin filaments have been demonstrated to play important roles in cell motility, and their dynamic rearrangement during cell motility is regulated by diverse cytoskeleton-associated proteins (Waterman-Storer and Salmon, 1999; Olson and Sahai, 2009).
Genetic and phenotypic analyses have shown that M. xanthus gliding motility is regulated by the A (adventurous) and the S (social) motility systems [9], [10].
Cell motility is regulated in part by the differential expression and function of cell adhesion molecules expressed on the cell surface [29].
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We are interested in determining how stromule morphology and motility are regulated by the plant cell.
Furthermore, in non-serum-deprived conditions (ND), the basal level of cellular motility was regulated opposite to that observed during deprivation by these mutant constructs.
Multiple processes involved in cell motility are regulated by growth factors and their receptors, such as EGFR (Wells et al, 2006).
Six genes involved in secretion and cell motility are regulated by low temperature treatments (Fig. 4, group N; Additional file 6).
The combination of gene expression profiling, proteomics and bioinformatical approaches as applied to these cell lines are necessary to better understand potential pathways through which MT1 expression and cell motility are regulated, and are likely to reveal new therapeutic targets for ovarian cancer.
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