Tiam1 expression is required to support cell movement in the more-motile cell lines, but is not sufficient to induce motility in a less-invasive cell line.
Figure 7: Recording of pharyngoesophageal motility in a patient with dysphagia due to a cricopharyngeal bar.
Petrie, R.J., Koo, H. & Yamada, K.M. Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix.
Zlosnik, J. E. et al. Swimming motility in a longitudinal collection of clinical isolates of Burkholderia cepacia complex bacteria from people with cystic fibrosis.
Compared to cells infected with the control viral vector, both KIF11 knockdown cell lines displayed a 14 45% increase in cell motility in a scratch wound healing assay.
Moreover, co-presentation of the cyclic RGD peptide as integrin ligand along with HS-bound CXCL12α led to enhanced spreading and motility, in a way that indicates cooperation between CXCR4 (the CXCL12α receptor) and integrins (the RGD receptors).
Fibulin-5 is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo.
To determine normative levels of inhibin B and examine levels in relationship to FSH, sperm count, and motility in a cohort of fertile and infertile men from the Northeast United States.
Our findings identify FBLN-5 as a novel TGF-beta-inducible target gene that regulates cell growth and motility in a context-specific manner and affects protein kinase activation by TGF-beta.
Treatment of a RON-positive adenosquamous carcinoma cell line with MSP additionally resulted in increased motility in a cell-migration assay, suggesting that MSP might promote cell migration of some NSCLCs.
The same researchers identified a Ca2+-binding protein (CaM) with MW of 18 kDa and pI 4.0 that regulates the flagellar motility in a calcium dependent manner by modifying both the sliding velocity and flagellar waveform (Morita et al. [2003, 2004, 2006]).
