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Adhesion, shape, motility, differentiation, and ultimately, cell function or apoptosis, can be steered by engineered surfaces.
FAK can activate CrK/CAS, PI3K and Grb2/Ras cell signaling pathways to regulate cell proliferation, motility, differentiation and intracellular trafficking [16].
The S100a8 protein belongs to the S100 family of proteins involved in the regulation of calcium dependent intracellular processes and is implicated in diverse cellular and molecular processes including protein phosphorylation, transcription, cell-cycle regulation, cell growth, motility, differentiation and survival, as well as, inflammation [30][47].
SH2B1 contains several protein-protein interaction domains that have been implicated in regulating actin, cell motility, differentiation and gene expression (Fig. 1 ).
Cell polarization is an important part of the response of eukaryotic cells to stimuli, and forms a primary step in cell motility, differentiation, and many cellular functions.
This process helps to understand the organization and function of this key cellular structure and provides insight into cell motility, differentiation, and apoptosis [ 13].
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PAKs are associated with a wide variety is cellular functions, including regulation of the MAPK pathway, cytoskeletal regulation and motility, differentiation, carcinogenesis and tumor invasion [ 129- 131].
Snail is one of the zinc-finger transcription factors and involved in various cellular functions, including cell motility, differentiation, proliferation and survival (Nieto 2002).
Phosphorylation of filamin A occurs in response to various cell signaling cascades that regulate cell motility, differentiation, apoptosis and inflammation.
Phosphorylation of filamin A occurs in response to various cell signaling cascades that regulate cell motility, differentiation, apoptosis and inflammation, which may be relevant to ureaplasmal disease pathogenesis.
Allam et al. [ 6] in their study on bladder tissue from animals actively colonized by U. parvum demonstrated significant alterations in actin binding proteins that may influence cell signaling cascades regulating cell motility, differentiation, apoptosis, and inflammation.
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