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This indicated the effect of prodigiosin in bringing down the motility capacity which is very essential factor for pathogenicity.
Cellular motility capacity implies a dynamic regulation of the actin cytoskeleton and particularly those of the cortical network.
This suggests that P69 has a very low motility capacity while M12 endows with the high motility ability.
Moreover, motility capacity of these HCC cell lines [ 23] was positively correlated with Cav-1 expressions as shown in Table 1.
Twist1 induction of metastasis through EMT plays a central role in epithelium-based cancers but may not be the most relevant pathological effect in hematological malignancies, because they derive from cells with intrinsic motility capacity.
Cell migration assays showed that KYSE520 cells, which had been transfected with WDR66 siRNA, displayed a motility capacity of only 40% compared to the cells having been transfected with control siRNA (AllStar) after 16 hours.
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This is especially interesting considering their limited motility capacities [16].
Despite the limited motility capacities of Symbiodinium spp., short distance dispersal of free-living Symbiodinium spp. from the macroalgal areas to the corals could be achieved by their diurnal swimming behavior or localized hydrodynamic conditions.
When exposed to microenvironmental signals, these cancer stem cells would display motility capacities due to EMT, lending support to the notion of "mobile cancer stem cells" initially proposed by T. Brabletz [39].
In 2008, Rappa et al. investigated the effects of CD133 down-regulation in human metastatic melanoma, which result in slower cell growth, reduced cell motility, decreased capacity to form spheres under stem cell-like growth conditions and reduced capacity of the cells to metastasize.
Irradiated parasites maintain their viability as assessed by their motility and capacity to infect host cells in vitro.
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