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Cytoplasmic linker protein 170 (CLIP-170) is a microtubule-binding protein that regulates cell motility by modulating microtubule dynamics (Maekawa and Schiebel, 2004).
Several reports indicated that LuxS has an alternative role in regulation of motility by modulating flagellar transcription and flagellar biosynthesis [ 51, 52].
Thus, VOCCs and KCa1.1 act as important regulators of gastrointestinal motility by modulating membrane potential and Ca2+ influx, and changes in these ion channels greatly affect the contractility of smooth muscle.
BCR has Rho-GEF and Rac-GAP activity, strongly suggesting a main role in the regulation of cytoskeleton modeling and cell motility by modulating the activity of the Rho subfamily of small GTPases, such as Rac, cdc42 and Rho.
Next, we examined co-dependent gene expression relationships between CXCR7 and CXCR4, since in breast cancer cells CXCR7 is known to regulate CXCL12-mediated cell motility by modulating CXCR4 expression [ 37].
Because dynamic microtubules play major roles in motility by modulating the disassembly of focal adhesions and retraction of the trailing edge of migrating cells, increased stability conferred by the enhanced binding of phosphorylated MAP1B could reasonably account for many aspects of Syk's ability to limit the motility of highly invasive cancer cells.
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Besides direct regulation of the transcription of several COG N genes, RosR was also found to indirectly affect the expression of some motility genes by modulating rem expression.
Y4 agonism with PP is thought to mediate effects on appetite and energy balance by actions within the brainstem, resulting in modulation of digestive processes such as gastric secretion, motility and emptying by modulating vagal cholinergic pathways [25], [29].
Dysregulation of Src has been linked to oncogenesis process for many years [52], and it is also known to play a role in metastasis by modulating cell motility and invasive abilities in skin, breast and colon cancers [53].
PAK proteins are known to regulate cell motility involving focal adhesion dynamics by modulating paxillin.
The extinction of c-Cbl expression decreases osteoclast motility, adhesion and resorbing activity by modulating the degradation of Src kinase.
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motility by viewing
motility by serving
motility by facilitating
motility by remodelling
motility by increasing
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motility by inducing
motility by illuminating
motility by using
motility by screening
motility by swimming
motility by directing
motility by favoring
motility by regulating
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