Sentence examples for motility by interacting from inspiring English sources
The actin binding protein CapG modulates cell motility by interacting with the cytoskeleton.
ECM proteins, such as fibronectin, can synergistically bind integrins and syndecans and activate the cytoplasmic domain of this proteoglycan, controlling cell adhesion and motility by interacting with intracellular components [ 29, 30].
Previous studies demonstrated that AAH mediates its effects on cell motility by interacting with, and hydroxylating Notch and Jagged [ 7], and that a downstream target of Notch signaling is the effector gene, HES-1 [ 40, 41].
Therefore, increased expression of Nck2 in human primary melanoma cells may elicit protein interactions that re-wire signaling pathways in a fashion that alters focal adhesions and promotes cell motility by interacting with FAK and PINCH.
The small calcium-binding protein S100A4 was known to enhance cell motility by interacting with non-muscle myosin II and was described to selectively stimulate cell motility in mouse mammary carcinoma cell lines without increasing in vitro invasiveness [ 39, 46, 47].
We previously reported that the molecular chaperone heat shock protein 90 (Hsupportspports GBM cell motility, in part by interacting with EphA2 and modulating receptor stability and function [9].
Particularly, CD151 contributes to integrin-dependent cell adhesion and motility by directly interacting with laminin-binding integrins (α3 β1, α6 β1, α6 β4, and α7 β1) (Hemler, 2008).
PAI-1 overexpressed up to approximately ten times more than normal level increases motility of cancer cells by interacting with vitronectin and other proteins.
Overexpressed P-cadherin increases motility of pancreatic cancer cells by interacting with p120ctn and subsequent activation of RHO GTPases [ 36].
26 demonstrate that P-cadherin overexpression promotes the motility of pancreatic cancer cells by interacting with p120ctn and, consequently, activating Rho-family GTPases, Rac1 and Cdc42.
A scaffolding protein best known for its actin-binding and cell motility function, FLNA also regulates cell signaling by interacting with a variety of receptors and signaling molecules [10], [11].
