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Disruption of these adhesion events leads to increased cell motility and potential invasiveness trough remodelling of the extra cellular matrix.
For live cell analysis of mitochondria motility and potential the flat cells with better distributed mitochondria were usually used.
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in vitro experiments showed that CXCR4 activation by SDF-1 regulates motility and metastatic potential of neoplastic epithelial cell lines [ 20, 21], while CXCR4 inhibitors are effective in reducing chemotactic and metastatic potential of this receptor [ 20].
Here, we examined the motility and fertilization potential of cryopreserved, thawed (frozen-thawed) sperm from previously cold-stored mouse epididymides.
We previously reported that cold storage of mouse epididymides in Lifor® perfusion medium prolonged sperm motility and fertilization potential and that the sperm efficiently fertilized oocytes when reduced glutathione was added to the fertilization medium.
The actin cytoskeleton is a primary determinant of tumor cell motility and metastatic potential.
Interestingly, HCT116 showed a higher motility and invasive potential than HT29 cells (Figure 5, panels B and C).
Moesin resides at the nexus of multiple pathways regulating cell attachment with the extracellular matrix and with nearby cells, cell motility and metastatic potential as well as cell survival.
This in turn promotes MMP-9 activity, which increases cancer cell motility and metastatic potential.
Depletion of PRL-3 resulted in reduced invasion, motility, and tumorigenic potential of A2780 ovarian cancer cells.
Mitochondrial dynamics were delineated into four categories (M1-M4) based on characteristics including distribution, motility, and membrane potential (ΔΨm).
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