Sentence examples for motility and hyperactivation from inspiring English sources
Therefore, these enzymes affect motility and hyperactivation of human spermatozoa [ 62].
These results suggest that endogenous ATP levels, motility and hyperactivation are coupled processes.
Our findings demonstrate that exogenous pyruvate is a potent activator of sperm motility and hyperactivation.
These results demonstrate that pyruvate-stimulated motility and hyperactivation correlate with increased tyrosine phosphorylation and endogenous ATP levels.
Our goal was to investigate the effect of pyruvate on motility and hyperactivation of human spermatozoa in combination with glucose.
The treatment of human spermatozoa with exogenous pyruvate increased intracellular ATP levels, progressive motility and hyperactivation by 56, 21 and 130%, respectively.
Conclusion: Sperm cells mildly heated at 40°C responded with greater motility, progression, and hyperactivation.
To test this, we treated human spermatozoa under capacitating conditions with increasing concentrations of oxamate, a known competitive substrate inhibitor of LDH (Adams et al., 1973; Wong et al., 1997), for 120 min. This resulted in a dose-dependent reduction in normal- and progressive motility, VCL, hyperactivation and ATP levels (Fig. 8).
Purified human spermatozoa from healthy donors were incubated under capacitating conditions (including albumin, bicarbonate and glucose) and tested for changes in ATP levels, motility, hyperactivation and tyrosine phosphorylation after treatment with pyruvate.
The simplest interpretation is that CatSpers are critical for the alteration of motility patterns for chemotaxis (sea urchin) and hyperactivation (mammals), but that the type of K channel activated (CNG or mSlo3) modulates CatSper's roles specific to the species.
CatSper-null sperm show no detectable Ca2+ current, defective calcium signalling, ATP depletion and abnormalities in motility (including hyperactivation; HA).
